KEGG   Mycobacterium tuberculosis H37Rv: Rv0667
Entry
Rv0667            CDS       T00015                                 
Symbol
rpoB
Name
(RefSeq) DNA-directed RNA polymerase subunit beta
  KO
K03043  DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
Organism
mtu  Mycobacterium tuberculosis H37Rv
Pathway
mtu03020  RNA polymerase
Brite
KEGG Orthology (KO) [BR:mtu00001]
 09120 Genetic Information Processing
  09121 Transcription
   03020 RNA polymerase
    Rv0667 (rpoB)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:mtu03021]
    Rv0667 (rpoB)
   03400 DNA repair and recombination proteins [BR:mtu03400]
    Rv0667 (rpoB)
Enzymes [BR:mtu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.7  Nucleotidyltransferases
    2.7.7.6  DNA-directed RNA polymerase
     Rv0667 (rpoB)
Transcription machinery [BR:mtu03021]
 Prokaryotic type
  Bacterial type
   RNA polymerase
    Core subunits
     Rv0667 (rpoB)
DNA repair and recombination proteins [BR:mtu03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   NER (nucleotide excision repair)
    TCR (transcription coupled repair) factors
     DNA-directed RNA polymerase complex (RNAP)
      Rv0667 (rpoB)
SSDB
Motif
Pfam: RNA_pol_Rpb2_6 RNA_pol_Rpb2_45 RNA_pol_Rpb2_3 RNA_pol_Rpb2_2 RNA_pol_Rpb2_7 RNA_pol_Rpb2_1 Peptidase_M23 RnfC_N
Other DBs
NCBI-GeneID: 888164
NCBI-ProteinID: NP_215181
TubercuList: Rv0667
UniProt: P9WGY9
Structure
Position
759807..763325
AA seq 1172 aa
MADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIG
SPRWRESAAERGDVNPVGGLEEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKD
MTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTFIINGTERVVVSQLVRSPGVY
FDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSE
QIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRY
DLARVGRYKVNKKLGLHVGEPITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVE
TDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTTQDVEAITPQTLINIRPVVAA
IKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPI
ETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLTADEEDRHVVAQANS
PIDADGRFVEPRVLVRRKAGEVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRAL
MGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEESGVIEEVSADYITVMHDNGT
RRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPW
EGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDE
RGIVRIGAEVRDGDILVGKVTPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGK
VIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLAGRHGNKGVIGKILPVEDMPF
LADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEA
QPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVG
YMYIMKLHHLVDDKIHARSTGPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQ
ELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLKELQSLCLNVEVLSSDGAAIE
LREGEDEDLERAAANLGINLSRNESASVEDLA
NT seq 3519 nt   +upstreamnt  +downstreamnt
ttggcagattcccgccagagcaaaacagccgctagtcctagtccgagtcgcccgcaaagt
tcctcgaataactccgtacccggagcgccaaaccgggtctccttcgctaagctgcgcgaa
ccacttgaggttccgggactccttgacgtccagaccgattcgttcgagtggctgatcggt
tcgccgcgctggcgcgaatccgccgccgagcggggtgatgtcaacccagtgggtggcctg
gaagaggtgctctacgagctgtctccgatcgaggacttctccgggtcgatgtcgttgtcg
ttctctgaccctcgtttcgacgatgtcaaggcacccgtcgacgagtgcaaagacaaggac
atgacgtacgcggctccactgttcgtcaccgccgagttcatcaacaacaacaccggtgag
atcaagagtcagacggtgttcatgggtgacttcccgatgatgaccgagaagggcacgttc
atcatcaacgggaccgagcgtgtggtggtcagccagctggtgcggtcgcccggggtgtac
ttcgacgagaccattgacaagtccaccgacaagacgctgcacagcgtcaaggtgatcccg
agccgcggcgcgtggctcgagtttgacgtcgacaagcgcgacaccgtcggcgtgcgcatc
gaccgcaaacgccggcaaccggtcaccgtgctgctcaaggcgctgggctggaccagcgag
cagattgtcgagcggttcgggttctccgagatcatgcgatcgacgctggagaaggacaac
accgtcggcaccgacgaggcgctgttggacatctaccgcaagctgcgtccgggcgagccc
ccgaccaaagagtcagcgcagacgctgttggaaaacttgttcttcaaggagaagcgctac
gacctggcccgcgtcggtcgctataaggtcaacaagaagctcgggctgcatgtcggcgag
cccatcacgtcgtcgacgctgaccgaagaagacgtcgtggccaccatcgaatatctggtc
cgcttgcacgagggtcagaccacgatgaccgttccgggcggcgtcgaggtgccggtggaa
accgacgacatcgaccacttcggcaaccgccgcctgcgtacggtcggcgagctgatccaa
aaccagatccgggtcggcatgtcgcggatggagcgggtggtccgggagcggatgaccacc
caggacgtggaggcgatcacaccgcagacgttgatcaacatccggccggtggtcgccgcg
atcaaggagttcttcggcaccagccagctgagccaattcatggaccagaacaacccgctg
tcggggttgacccacaagcgccgactgtcggcgctggggcccggcggtctgtcacgtgag
cgtgccgggctggaggtccgcgacgtgcacccgtcgcactacggccggatgtgcccgatc
gaaacccctgaggggcccaacatcggtctgatcggctcgctgtcggtgtacgcgcgggtc
aacccgttcgggttcatcgaaacgccgtaccgcaaggtggtcgacggcgtggttagcgac
gagatcgtgtacctgaccgccgacgaggaggaccgccacgtggtggcacaggccaattcg
ccgatcgatgcggacggtcgcttcgtcgagccgcgcgtgctggtccgccgcaaggcgggc
gaggtggagtacgtgccctcgtctgaggtggactacatggacgtctcgccccgccagatg
gtgtcggtggccaccgcgatgattcccttcctggagcacgacgacgccaaccgtgccctc
atgggggcaaacatgcagcgccaggcggtgccgctggtccgtagcgaggccccgctggtg
ggcaccgggatggagctgcgcgcggcgatcgacgccggcgacgtcgtcgtcgccgaagaa
agcggcgtcatcgaggaggtgtcggccgactacatcactgtgatgcacgacaacggcacc
cggcgtacctaccggatgcgcaagtttgcccggtccaaccacggcacttgcgccaaccag
tgccccatcgtggacgcgggcgaccgagtcgaggccggtcaggtgatcgccgacggtccc
tgtactgacgacggcgagatggcgctgggcaagaacctgctggtggccatcatgccgtgg
gagggccacaactacgaggacgcgatcatcctgtccaaccgcctggtcgaagaggacgtg
ctcacctcgatccacatcgaggagcatgagatcgatgctcgcgacaccaagctgggtgcg
gaggagatcacccgcgacatcccgaacatctccgacgaggtgctcgccgacctggatgag
cggggcatcgtgcgcatcggtgccgaggttcgcgacggggacatcctggtcggcaaggtc
accccgaagggtgagaccgagctgacgccggaggagcggctgctgcgtgccatcttcggt
gagaaggcccgcgaggtgcgcgacacttcgctgaaggtgccgcacggcgaatccggcaag
gtgatcggcattcgggtgttttcccgcgaggacgaggacgagttgccggccggtgtcaac
gagctggtgcgtgtgtatgtggctcagaaacgcaagatctccgacggtgacaagctggcc
ggccggcacggcaacaagggcgtgatcggcaagatcctgccggttgaggacatgccgttc
cttgccgacggcaccccggtggacattattttgaacacccacggcgtgccgcgacggatg
aacatcggccagattttggagacccacctgggttggtgtgcccacagcggctggaaggtc
gacgccgccaagggggttccggactgggccgccaggctgcccgacgaactgctcgaggcg
cagccgaacgccattgtgtcgacgccggtgttcgacggcgcccaggaggccgagctgcag
ggcctgttgtcgtgcacgctgcccaaccgcgacggtgacgtgctggtcgacgccgacggc
aaggccatgctcttcgacgggcgcagcggcgagccgttcccgtacccggtcacggttggc
tacatgtacatcatgaagctgcaccacctggtggacgacaagatccacgcccgctccacc
gggccgtactcgatgatcacccagcagccgctgggcggtaaggcgcagttcggtggccag
cggttcggggagatggagtgctgggccatgcaggcctacggtgctgcctacaccctgcag
gagctgttgaccatcaagtccgatgacaccgtcggccgcgtcaaggtgtacgaggcgatc
gtcaagggtgagaacatcccggagccgggcatccccgagtcgttcaaggtgctgctcaaa
gaactgcagtcgctgtgcctcaacgtcgaggtgctatcgagtgacggtgcggcgatcgaa
ctgcgcgaaggtgaggacgaggacctggagcgggccgcggccaacctgggaatcaatctg
tcccgcaacgaatccgcaagtgtcgaggatcttgcgtaa

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (1)   
   KEGG PATHWAY (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (19)   
   KEGG ORTHOLOGY (1)   
   RefGene (14)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
   TUBERCULIST (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
3D Structure (71)   
   PDB (71)   
Protein domain (8)   
   Pfam (8)   
All databases (108)   

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